AZD3229
AZD3229 (AZD-3229) is a potent, pan-KIT mutant inhibitor with potent single digit nM growth inhibition against a diverse panel of mutant KIT driven Ba/F3 cell lines (GI50=1-50 nM) ; shows good margin to KDR-driven effects, also inhibits PDGFR mutants (Tel-PDGFRα, Tel-PDGFRβ, V561D/D842V) .
Product Specifications
CAS Number
2248003-60-1
Product Name Alternative
AZD-3229 | AZD 3229
Purity
>98% (HPLC)
Solubility
DMSO: 95 mg/mL (198.12 mM) ; Water: Insoluble (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (NC1=CC=C (NC2=C3C (F) =CC (OCCOC) =CC3=NC=N2) C=C1) CN4N=NC (C (C) C) =C4
Molecular Formula
C24H26FN7O3
Molecular Weight
479.516
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (4-{[5-Fluoro-7- (2-methoxyethoxy) quinazolin-4-yl]-amino}phenyl) -2-[4- (propan-2-yl) -1H-1,2,3-triazol-1-yl]-acetamide
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