Catalpol
Catalpol, an iridoid glycoside, has neuroprotective, anti-inflammatory, and anti-hepatitis virus effects. (In Vitro) :Catalpol (0.1 μg/mL; for 3 days) can induce neuronal differentiation in PC12 cells through activation of the intracellular signal transduction pathway, and promote neurite length. (In Vivo) :Catalpol (25-100 mg/kg; intraperitoneal injection; once) treatment clearly reduces blood urea nitrogen, serum creatinine levels and the expression of KIM-1 in renal ischemia/reperfusion-injury (IRI) mice. Catalpol markedly reduces the expression of PI3K, Akt and eNOS levels, and suppresses the TNF-α, IL-1β, IL-6 and IL-10 activities.
Product Specifications
CAS Number
2415-24-9
Product Name Alternative
Catalpinoside | 7,8-epoxy Aucubin
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
[H][C@]1 ([C@H] (O) [C@@]2 ([H]) [C@]3 (CO) O2) [C@]3 ([H]) [C@H] (O[C@H]4[C@H] (O) [C@@H] (O) [C@H] (O) [C@@H] (CO) O4) OC=C1
Molecular Formula
C15H22O10
Molecular Weight
362.33
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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