Leonurine
Leonurine (SCM-198) is a natural alkaloid that exhibits cardio-and neuronal-protective effects both in vitro and in vivo, occupies the caspase recruitment site of Apaf-1, blocks its interaction with procaspase-9; attenuates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells, protects middle cerebral artery occluded rats through antioxidant effect and regulation of mitochondrial function, attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4 (Nox4) .
Product Specifications
CAS Number
24697-74-3
Product Name Alternative
SCM-198
Purity
>98% (HPLC)
Solubility
DMSO : 6 mg/mL 19.27 mM
Smiles
O=C (OCCCCNC (N) =N) C1=CC (OC) =C (O) C (OC) =C1
Molecular Formula
C14H21N3O5
Molecular Weight
311.338
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Benzoic acid, 4-hydroxy-3,5-dimethoxy-, ester with (4-hydroxybutyl) guanidine (8CI)
Available Sizes
Frequently Asked Questions
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5 L Single-Use Storage Bottle (G)