Isomangiferin
Isomangiferin is the major tetracyclic oxindole alkaloid components of Uncaira species, inhibits NMDA receptor with IC50 of 43.2 uM, also blocks calcium channel; also effectively blocks the EphA4-dependent signaling in hippocampal neurons, reduces the EphA4 activity effectively in the hippocampus of APP/PS1 transgenic mice after oral administration, restores the impaired long-term potentiation in transgenic mouse models of AD.
Product Specifications
CAS Number
24699-16-9
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
C1=C2C (=CC (=C1O) O) OC3=C (C2=O) C (=CC (=C3C4C (C (C (C (O4) CO) O) O) O) O) O
Molecular Formula
C19H18O11
Molecular Weight
422.3396
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4-beta-D-Glucopyranosyl-1,3,6,7-tetrahydroxy-9H-xanthen-9-one
Available Sizes
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