Cyclo (RGDyK) trifluoroacetate
Cyclo (RGDyK) (Cyclic Arg-Gly-Asp-D-Tyr-Lys) is a cyclic derivative of RGD, potent, selective αVβ3 integrin inhibitor with IC50 of 20 nM; a recognition motif used by extracellular matrix proteins (vitronectin, fibrinogen, laminin, and collagen) to bind to a variety of integrins including αvβ3. (In Vitro) :Cyclo (RGDyK) (c (RGDyK (SAA) ) shows high affinity and selectivity for αVβ3 over αVβ5 (IC50=4000 nM) and αIIbβ3 (IC50=3000 nM) .
Product Specifications
CAS Number
250612-42-1
Product Name Alternative
Cyclic Arg-Gly-Asp-D-Tyr-Lys
Purity
>98% (HPLC)
Solubility
DMSO: 94 mg/mL (110.9 mM) Water: 94 mg/mL (110.9 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
Molecular Formula
C31H43F6N9O12
Molecular Weight
847.72
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Cyclo (L-arginylglycyl-L-α-aspartyl-D-tyrosyl-L-lysyl), bis (trifluoroacetate) (salt) (9CI)
Available Sizes
Frequently Asked Questions
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