Tasquinimod
An orally active antiangiogenic agent with anti-prostate cancer activity, an allosteric modulator of HDAC4 with Kd of 10-30 nM; inhibits colocalization of N-CoR/HDAC3, thereby inhibiting deacetylation of histones and HDAC4 client transcription factors, such as HIF-1α.Prostate cancer Phase 3 Clinical.
Product Specifications
CAS Number
254964-60-8
Product Name Alternative
ABR-215050 | ABR215050 | ABR 215050
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 42 mg/mL
Smiles
O=C (C1=C (O) C2=C (N (C) C1=O) C=CC=C2OC) N (C) C3=CC=C (C (F) (F) F) C=C3
Molecular Formula
C20H17F3N2O4
Molecular Weight
406.3552
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-Quinolinecarboxamide, 1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4- (trifluoromethyl) phenyl]-
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