NSC 377071
NSC 377071 (NSC-377071, NSC377071, Cambendazole) is a novel ATG4B antagonist that inhibits autophagy, with no effect on mTOR and PI3K activities; directly inhibits cellular ATG4B activity induced by starvation or rapamycin and suppresses the lipidation of LC3B and autophagosome formation in response to starvation, suppresses Saos-2 osteosarcoma growth in vivo.
Product Specifications
CAS Number
26097-80-3
Product Name Alternative
NSC-377071 | NSC377071 | Cambendazole
Field of Research
Neuroscience
Purity
>98% (HPLC)
Solubility
DMSO: Soluble (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (OC (C) C) NC1=CC=C2C (N=C (C3=CSC=N3) N2) =C1
Molecular Formula
C14H14N4O2S
Molecular Weight
302.352
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Propan-2-yl N-[2- (1,3-thiazol-4-yl) -3H-benzimidazol-5-yl]carbamate
Available Sizes
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