SKF 81297 (hydrobromide)

SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist[1].

Product Specifications

CAS Number

[67287-39-2]

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/skf-81297-hydrobromide.html

Purity

99.88

Solubility

DMF : ≥ 20 mg/mL|DMSO : 100 mg/mL (ultrasonic) |Ethanol : ≥ 2 mg/mL

Smiles

OC1=CC2=C(C(Cl)=C1O)CCNCC2C3=CC=CC=C3.Br

Molecular Formula

C16H17BrClNO2

Molecular Weight

370.67

References & Citations

[1]Vermeulen RJ, et al. The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys. Eur J Pharmacol. 1993 Apr 22;235 (1) :143-7.|[2]Auger ML, et al. Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D1 agonists SKF-81297 and d-Govadine. Neuropharmacology. 2020 Jan 1;162:107844.