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SKF 81297 (hydrobromide)

Product Specifications

UNSPSC Description

SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist[1].

Target Antigen

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/skf-81297-hydrobromide.html

Purity

99.62

Solubility

DMF : ≥ 20 mg/mL|DMSO : ≥ 20 mg/mL|DMSO : 120 mg/mL (ultrasonic)|Ethanol : ≥ 2 mg/mL

Smiles

OC1=CC2=C(C(Cl)=C1O)CCNCC2C3=CC=CC=C3.Br

Molecular Weight

370.67

References & Citations

[1]Vermeulen RJ, et al. The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys. Eur J Pharmacol. 1993 Apr 22;235(1):143-7.|[2]Auger ML, et al. Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D1 agonists SKF-81297 and d-Govadine. Neuropharmacology. 2020 Jan 1;162:107844.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-12236/SKF-81297-hydrobromide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-12236/SKF-81297-hydrobromide-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

67287-39-2

Available Sizes

Curated Selection

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