SKF 81297 (hydrobromide)
SKF 81297 hydrobromide is a potent and selective dopamine D1 receptor agonist[1].
Product Specifications
CAS Number
[67287-39-2]
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/skf-81297-hydrobromide.html
Purity
99.88
Solubility
DMF : ≥ 20 mg/mL|DMSO : 100 mg/mL (ultrasonic) |Ethanol : ≥ 2 mg/mL
Smiles
OC1=CC2=C(C(Cl)=C1O)CCNCC2C3=CC=CC=C3.Br
Molecular Formula
C16H17BrClNO2
Molecular Weight
370.67
References & Citations
[1]Vermeulen RJ, et al. The selective dopamine D1 receptor agonist, SKF 81297, stimulates motor behaviour of MPTP-lesioned monkeys. Eur J Pharmacol. 1993 Apr 22;235 (1) :143-7.|[2]Auger ML, et al. Amelioration of cognitive impairments induced by GABA hypofunction in the male rat prefrontal cortex by direct and indirect dopamine D1 agonists SKF-81297 and d-Govadine. Neuropharmacology. 2020 Jan 1;162:107844.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D1 Receptor
Available Sizes
Curated Selection
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