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AICAR

AICAR (Acadesine, AICA Riboside, NSC 105823) is a selective AMPK activator in both hepatocytes and adipocytes; inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes at 0.5 mM, inhibits insulin-stimulated glucose and reduces GLUT4 translocation in 3T3-L1 adipocytes; down-regulates the insulin receptor expression in HepG2 cells.

Product Specifications

CAS Number

2627-69-2

Product Name Alternative

Acadesine | AICA Riboside

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 30 mg/mL

Smiles

O=C (C1=C (N) N ([C@@H]2O[C@H] (CO) [C@@H] (O) [C@H]2O) C=N1) N

Molecular Formula

C9H14N4O5

Molecular Weight

258.2

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1H-Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-

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