Pardoprunox
Pardoprunox (SLV-308) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist; D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist (IA = 50% and 67%, respectively) and 5-HT1A receptor (pKi = 8.5) full agonist (IA = 100%) ; also binds to D4 (pKi = 7.8), α1-adrenergic (pKi = 7.8), α2-adrenergic (pKi = 7.4), and 5-HT7 receptors (pKi = 7.2) with lower affinity.
Product Specifications
CAS Number
269718-84-5
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
CN1CCN (CC1) C1=CC=CC2=C1OC (=O) N2
Molecular Formula
C12H15N3O2
Molecular Weight
233.27
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
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