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Etidronate

Etidronate (Didronel) is a human protein tyrosine phosphatase inhibitor. (In Vitro) :Etidronic acid (Etidronate) (10 mM, 24 h) shows cytotoxicity, causes a decrease in the S-phase population and an increase in the G2/M population, induces p53 mutation in MCF-7 cells.Etidronic acid (100 nM, 24 h) induces osteoclast apoptosis, which displays characteristics of apoptosis, including chromatin condensation and changed cellular and nuclear morphology, detected by fluorescence microscopy.

Product Specifications

CAS Number

2809-21-4

Purity

>98% (HPLC)

Solubility

Water: 41 mg/mL (199.0 mM)

Smiles

CC (O) (P (=O) (O) O) P (=O) (O) O

Molecular Formula

C2H8O7P2

Molecular Weight

206.03

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

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