STAT5-IN-1
A selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays; shows little to no inhibition for STAT1, STAT3 and Lck (<40% inhibition at 500 uM) ; selectively inhibits the function of the STAT5b domain and STAT5 DNA binding in vitro, and selectively inhibits activation of STAT5 in K562 cells.
Product Specifications
CAS Number
285986-31-4
Product Name Alternative
Signal Transducers and Activators of Transcription 5
Purity
>98% (HPLC)
Solubility
DMSO: ≥23.0 mg/mL (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (N/N=C/C1=COC2=C (C=CC=C2) C1=O) C3=CN=CC=C3
Molecular Formula
C16H11N3O3
Molecular Weight
293.28
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
3-Pyridinecarboxylic acid, [ (4-oxo-4H-1-benzopyran-3-yl) methylene]hydrazide (9CI)
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