SU-9516
A selective CDK2 inhibitor with IC50 of 22 nM; shows less potent for CDK1/CDK4 (IC50=40/200 nM), no inhibition on PKC, EGFR, p38MAPK; decreases the phosphorylation of pRb, and increases caspase-3 activation.
Product Specifications
CAS Number
377090-84-1
Product Name Alternative
SU9516 | SU 9516
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C1NC2=C (C=C (OC) C=C2) /C1=C/C3=CN=CN3
Molecular Formula
C13H11N3O2
Molecular Weight
241.2453
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2H-Indol-2-one, 1,3-dihydro-3- (1H-imidazol-5-ylmethylene) -5-methoxy-, (3Z) -
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