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SU-9516

A selective CDK2 inhibitor with IC50 of 22 nM; shows less potent for CDK1/CDK4 (IC50=40/200 nM), no inhibition on PKC, EGFR, p38MAPK; decreases the phosphorylation of pRb, and increases caspase-3 activation.

Product Specifications

CAS Number

377090-84-1

Product Name Alternative

SU9516 | SU 9516

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

O=C1NC2=C (C=C (OC) C=C2) /C1=C/C3=CN=CN3

Molecular Formula

C13H11N3O2

Molecular Weight

241.2453

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

2H-Indol-2-one, 1,3-dihydro-3- (1H-imidazol-5-ylmethylene) -5-methoxy-, (3Z) -

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