Cridanimod
Cridanimod (10-carboxymethyl-9-acridanone, 10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route; displays extraordinary activity in phosphorylating IRF3 in the murine system; also increases progesterone receptor (PrR) expression in endometrial tissue.Ovarian Cancer Phase 2 Clinical (In Vivo) :Cridanimod (IM; 1-6 mg; twice a week) has a significantly longer survival time. Cridanimod significant increases in IFNα and -β in cridanimod-treated mice in a dose-dependent manner.
Product Specifications
CAS Number
38609-97-1
Product Name Alternative
10-carboxymethyl-9-acridanone | 10-CMA | XBIO-101
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 25 mg/mL, 98.7 mM (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
C1=CC=C2C (=C1) C (=O) C3=CC=CC=C3N2CC (=O) O
Molecular Formula
C15H11NO3
Molecular Weight
253.25
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- (9-oxoacridin-10-yl) acetic acid
Available Sizes
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Double tray HxDxW 280x420x139mm, 2 trays w/ handel and lid