Chelerythrine chloride
Chelerythrine chloride is a potent, cell-permeable inhibitor of PKC (IC50=66 nM) and p38 MAPK, also inhibits the Bcl-XL-Bak BH3 peptide binding with IC50 of 1.5 uM and displaces Bax from Bcl-XL; inhibits LPS-induced TNF-α level and NO production in LPS-induced murine peritoneal macrophages through selective inhibition of p38 MAPK and ERK1/2 activation; triggers apoptosis via direct action on mitochondria.
Product Specifications
CAS Number
3895-92-9
Product Name Alternative
Broussonpapyrine chloride | NSC 646662
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 3.9 mg/mL
Smiles
C[N+]1=C2C (=C3C=CC (=C (C3=C1) OC) OC) C=CC4=CC5=C (C=C42) OCO5.[Cl-]
Molecular Formula
C21H18ClNO4
Molecular Weight
383.8249
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1,2-Dimethoxy-12-methyl[1,3]benzodi oxolo[5,6-c]phenanthridinium chloride
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Rat S100 Calcium Binding Protein A10 (S100A10) ELISA Kit
Rat S100 Calcium Binding Protein A10 (S100A10) ELISA Kit
LSM4, ID (LSM4, U6 snRNA-associated Sm-like protein LSm4, Glycine-rich protein) (PE) discontinued
