LY-364947
LY364947 is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM in a cell-free assay, shows 7-fold selectivity over TGFβR-II.
Product Specifications
CAS Number
396129-53-6
Product Name Alternative
HTS 466284 | TGF-β RI Kinase Inhibitor
Purity
>98% (HPLC)
Solubility
DMSO: 1 mg/mL (3.67 mM)
Smiles
C1 (C2=CNN=C2C3=NC=CC=C3) =CC=NC4=CC=CC=C14
Molecular Formula
C17H12N4
Molecular Weight
272.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (3- (pyridin-2-yl) -1H-pyrazol-4-yl) quinoline
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