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LY-364947

LY364947 is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM in a cell-free assay, shows 7-fold selectivity over TGFβR-II.

Product Specifications

CAS Number

396129-53-6

Product Name Alternative

HTS 466284 | TGF-β RI Kinase Inhibitor

Purity

>98% (HPLC)

Solubility

DMSO: 1 mg/mL (3.67 mM)

Smiles

C1 (C2=CNN=C2C3=NC=CC=C3) =CC=NC4=CC=CC=C14

Molecular Formula

C17H12N4

Molecular Weight

272.3

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4- (3- (pyridin-2-yl) -1H-pyrazol-4-yl) quinoline

Available Sizes

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