Penciclovir
A guanosine analogue antiviral agent used for the treatment of various herpesvirus (HSV) infections; inhibits viral DNA polymerase and exhibits low toxicity and good selectivity.HSV Infection Approved (In Vitro) :Penciclovir (0-100 μg/ml) shows anti-herpesvirus activity with EC50s of 0.5, 0.8, 2.4, 52, 100, 1.2, 1.6, 0.9, >100 μg/ml for HSV-1 (HFEM), HSV-2 (MS), VZV (Ellen), CMV (AD-169), BHV-1 (Oxford 1964), BHV-2 (New York 1), EHV-1 (Quai Hals), FHV-1 (B927), SVV, respectively.Penciclovir (0-100 μg/ml) shows no-toxic to uninfected human cells. (In Vivo) :Penciclovir (100 mg/kg; s.c.; daily for 5 days) preventes mortality in mouse.
Product Specifications
CAS Number
39809-25-1
Product Name Alternative
VSA-671 | BRL-39123
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 53 mg/mL
Smiles
C1=NC2=C (N1CCC (CO) CO) NC (=NC2=O) N
Molecular Formula
C10H15N5O3
Molecular Weight
253.2578
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
6H-Purin-6-one, 2-amino-1,9-dihydro-9-[4-hydroxy-3- (hydroxymethyl) butyl]-
Available Sizes
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