Belinostat
Belinostat is a novel hydroxamic acid-type histone deacetylase (HDAC) inhibitor with antineoplastic activity. Belinostat targets HDAC enzymes, thereby inhibiting tumor cell proliferation, inducing apoptosis, promoting cellular differentiation, and inhibiting angiogenesis. This agent may sensitize drug-resistant tumor cells to other antineoplastic agents, possibly through a mechanism involving the down-regulation of thymidylate synthase.
Product Specifications
CAS Number
414864-00-9
Product Name Alternative
PXD101
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 64 mg/mL (201.03 mM)
Smiles
C1=CC=C (C=C1) NS (=O) (=O) C2=CC=CC (=C2) /C=C/C (=O) NO
Molecular Formula
C15H14N2O4S
Molecular Weight
318.35
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Propenamide, N-hydroxy-3- (3- ((phenylamino) sulfonyl) phenyl) -
Available Sizes
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