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AK-7

A potent, selective and brain-permeable SIRT2 inhibitor with IC50 of 15.5 uM; reduces cholesterol in cultured naive neuronal cells and brain slices from wild-type mice; shows neuroprotective activity in Huntington's disease mouse models, and reduces cholesterol in neuronal models.

Product Specifications

CAS Number

420831-40-9

Product Name Alternative

AK 7 | AK7

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

O=C (NC1=CC=CC (Br) =C1) C2=CC=CC (S (=O) (N3CCCCCC3) =O) =C2

Molecular Formula

C19H21BrN2O3S

Molecular Weight

437.3506

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Benzamide, N- (3-bromophenyl) -3-[ (hexahydro-1H-azepin-1-yl) sulfonyl]-

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