Flunixin meglumin
Flunixin Meglumin is a potent inhibitor of the enzyme cyclooxygenase used as analgesic agent with anti-inflammatory and antipyretic activity. (In Vitro) :flunixin meglumine (10-1000 μM, 2 h) inhibits lipopolysaccharide (LPS) -induced activity of inducible nitric oxide synthase (iNOS) in RAW 264.7 murine macrophages.flunixin meglumine (10-1000 μM, 2 h) inhibits lipopolysaccharide-induced activation of nuclear factor kappa B (NfκB) in RAW 264.7 murine macrophages. (In Vivo) :Flunixin meglumine (intravenous injection; 1.1 mg/kg; once) treatment inhibits the formation of exudate PGE2 and serum TXB2.
Product Specifications
CAS Number
42461-84-7
Product Name Alternative
NIH 10250
Purity
>98% (HPLC)
Solubility
Ethanol: 8 mg/mL (16.27 mM) ; Water: 98 mg/mL (199.4 mM) ; DMSO: 98 mg/mL (199.4 mM)
Smiles
O=C (C1=CC=CN=C1NC2=CC=CC (C (F) (F) F) =C2C) O.O[C@H] ([C@H] ([C@@H] ([C@@H] (CO) O) O) O) CNC
Molecular Formula
C21H28F3N3O7
Molecular Weight
491.46
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(2R,3R,4R,5S) -6- (methylamino) hexane-1,2,3,4,5-pentaol 2- ((2-methyl-3- (trifluoromethyl) phenyl) amino) nicotinate
Available Sizes
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