BCI-121
BCI-121 (BCI121) is a substrate-competitive SMYD3 inhibitor that significantly inhibits SMYD3-substrate interaction and chromatin recruitment and is effective in reducing proliferation in various cancer cells types; impairs SMYD3-mediated H4 in vitro methylation, reduced proliferation of HT29 and HCT116 cells; reproduces the effects of SMYD3-targeted RNAi.
Product Specifications
CAS Number
432529-82-3
Product Name Alternative
BCI 121 | BCI121
Purity
>98% (HPLC)
Solubility
DMSO: 100 mg/mL, 293.93 mM (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=C (NC1=CC=C (Br) C=C1) CN2CCC (C (N) =O) CC2
Molecular Formula
C14H18BrN3O2
Molecular Weight
340.22
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
4- (Aminocarbonyl) -N- (4-bromophenyl) -1-piperidineacetamide
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