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BCI-121

BCI-121 (BCI121) is a substrate-competitive SMYD3 inhibitor that significantly inhibits SMYD3-substrate interaction and chromatin recruitment and is effective in reducing proliferation in various cancer cells types; impairs SMYD3-mediated H4 in vitro methylation, reduced proliferation of HT29 and HCT116 cells; reproduces the effects of SMYD3-targeted RNAi.

Product Specifications

CAS Number

432529-82-3

Product Name Alternative

BCI 121 | BCI121

Purity

>98% (HPLC)

Solubility

DMSO: 100 mg/mL, 293.93 mM (< 1 mg/ml refers to the product slightly soluble or insoluble)

Smiles

O=C (NC1=CC=C (Br) C=C1) CN2CCC (C (N) =O) CC2

Molecular Formula

C14H18BrN3O2

Molecular Weight

340.22

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4- (Aminocarbonyl) -N- (4-bromophenyl) -1-piperidineacetamide

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