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Kobe0065

Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD; exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.

Product Specifications

CAS Number

436133-68-5

Product Name Alternative

Kobe0065 | Kobe 0065 | Kobe0065

Purity

>98% (HPLC)

Solubility

DMSO: 10 mM

Smiles

FC (C1=CC ([N+] ([O-]) =O) =C (NNC (NC2=CC=C (C) C (Cl) =C2) =S) C ([N+] ([O-]) =O) =C1) (F) F

Molecular Formula

C15H11ClF3N5O4S

Molecular Weight

449.79

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

N- (3-chloro-4-methylphenyl) -2- (2,6-dinitro-4- (trifluoromethyl) phenyl) hydrazinecarbothioamide.

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