Kobe0065
Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD; exhibits potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.
Product Specifications
CAS Number
436133-68-5
Product Name Alternative
Kobe0065 | Kobe 0065 | Kobe0065
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
FC (C1=CC ([N+] ([O-]) =O) =C (NNC (NC2=CC=C (C) C (Cl) =C2) =S) C ([N+] ([O-]) =O) =C1) (F) F
Molecular Formula
C15H11ClF3N5O4S
Molecular Weight
449.79
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (3-chloro-4-methylphenyl) -2- (2,6-dinitro-4- (trifluoromethyl) phenyl) hydrazinecarbothioamide.
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