CeMMEC1
CeMMEC1 is a potent, selective second bromodomain of TAF1 inhibitor with Kd of 1.8 uM; shows high selectivity for the TAF1 (2) bromodomain over BRD4 (1), BRD9, CREBBP, EP300 and TAF1 (2) bromodomains (IC50>10 uM; impaires cell viability in TAF1 downregulated cells; synergizes with (+) -JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
Product Specifications
CAS Number
440662-09-9
Product Name Alternative
CeMMEC 1
Purity
>98% (HPLC)
Solubility
DMSO: 21 mg/mL (62.4 mM) (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
CN1C=C (C2=CC=CC=C2C1=O) C (=O) NC3=CC4=C (C=C3) OCCO4
Molecular Formula
C19H16N2O4
Molecular Weight
336.3
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
N- (2,3-dihydro-1,4-benzodioxin-6-yl) -1,2-dihydro-2-methyl-1-oxo-4-isoquinolinecarboxamide
Available Sizes
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