CGP 57380
A cell-permeable, specific MNK1 inhibitor with IC50 of 2.2 uM; has no inhibitory activity on p38, JNK1, ERK1/2, etc.; inhibits phosphorylation of eIF4E in cellular assays with IC50 of 3 uM.
Product Specifications
CAS Number
522629-08-9
Product Name Alternative
CGP57380 | CGP-57380
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 43 mg/mL
Smiles
NC1=C2C (NN=C2NC3=CC=C (F) C=C3) =NC=N1
Molecular Formula
C11H9FN6
Molecular Weight
244.2278
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Pyrazolo[3,4-d]pyrimidine-3,4-diamine, N3- (4-fluorophenyl) -
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