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CGP 57380

A cell-permeable, specific MNK1 inhibitor with IC50 of 2.2 uM; has no inhibitory activity on p38, JNK1, ERK1/2, etc.; inhibits phosphorylation of eIF4E in cellular assays with IC50 of 3 uM.

Product Specifications

CAS Number

522629-08-9

Product Name Alternative

CGP57380 | CGP-57380

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 43 mg/mL

Smiles

NC1=C2C (NN=C2NC3=CC=C (F) C=C3) =NC=N1

Molecular Formula

C11H9FN6

Molecular Weight

244.2278

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1H-Pyrazolo[3,4-d]pyrimidine-3,4-diamine, N3- (4-fluorophenyl) -

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