Salinomycin
Salinomycin is an inhibitor of Wnt/β-catenin signaling, which acts on the Wnt/Fzd/LRP complex. Salinomycin strongly suppresses Wnt1-stimulated reporter activity with an IC50 of 163 nM, and reduces β-catenin levels.
Product Specifications
CAS Number
53003-10-4
Product Name Alternative
AHR 3096 | AHR3096 | AHR-3096 | K 364 | Salinomycin | BioCox | Sacox | Salocin | Coxistac
Purity
>98% (HPLC)
Solubility
DMSO:≥ 36.7mg/mL In vivo: Add solvents to the product individually and in order: 10% DMSO+40% PEG300+5% Tween-80+45% saline (clear) ≥2mg/mL ;10% DMSO+90% corn oil (clear) ≥2mg/mL
Smiles
CC[C@@H] (C (O) =O) [C@H]1CC[C@@H] ([C@H] ([C@H] ([C@@H] ([C@@H] (C ([C@@H] ([C@H]2O[C@]3 ([C@@H] (C[C@@H]2C) C) O[C@]4 ([C@@H] (C=C3) O) CC[C@] (O4) ([C@H]5CC[C@] (CC) ([C@@H] (O5) C) O) C) CC) =O) C) O) C) O1) C
Molecular Formula
C??H??O??
Molecular Weight
751
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
(R) -2- ((2R,5S,6R) -6- ((2S,3S,4S,6R) -6- ((2S,5S,7R,9S,10S,12R,15R) -2- ((2R,5R,6S) -5-ethyl-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl) -15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl) -3-hydroxy-4-methyl-5-oxooctan-2-yl) -5-methyltetrahydro-2H-pyran-2-yl) butanoic acid
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