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Rapamycin

A macrolide compound that has potent immunosuppressive and antiproliferative properties by inhibiting mTOR (IC50=0.1 nM) .Other Indication Approved (In Vitro) :Rapamycin (GMP) (1 nM; 2-3 weeks) induces in vitro differentiation of human embryonic stem cell (hESCs) into mineralized osteoblasts.Rapamycin (GMP) (1 nM; 2-3 weeks) enhances the osteoblastic differentiation of human embryoid bodies (hEBs) .Rapamycin (GMP) (20 nM; 4 h) serum-dependently promotes vascular smooth muscle cells (VSMCs) differentiation.Rapamycin (GMP) induces osteoblastic differentiation in rat osteoblast-like osteosarcoma cells.

Product Specifications

CAS Number

53123-88-9

Product Name Alternative

Sirolimus

Purity

>98% (HPLC)

Solubility

DMSO: ≥ 28 mg/mL

Smiles

C[C@@H] (C ([C@H] (OC) [C@H] (O) /C (C) =C/[C@@H] (C) C (C[C@@H] ([C@H] (C) C[C@@H]1CC[C@@H] (O) C (OC) C1) OC2=O) =O) =O) C[C@H] (C) /C=C/C=C/C=C (C) /[C@@H] (OC) C[C@H]3O[C@] (C (C (N4[C@H]2CCCC4) =O) =O) (O) [C@H] (C) CC3

Molecular Formula

C51H79NO13

Molecular Weight

914.1719

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Rapamycin

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