Acemetacin
Acemetacin (Emflex) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor. (In Vitro) :Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug, used for the treatment of osteoarthritis, rheumatoid arthritis, lower back pain, and relieving post-operative pain. Acemetacin (TVX 1322), a glycolic acid ester of indometacin, acts as a prodrug; in the body, it is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. An advantage of Acemetacin (TVX 1322) is that it reduces gastric damage when compared to indometacin.
Product Specifications
CAS Number
53164-05-9
Product Name Alternative
Acemetacin | Rantudil | K 708 | K-708 | K708
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
Ethanol: 58 mg/mL warmed (139.48 mM) ; DMSO: 83 mg/mL (199.6 mM)
Smiles
O=C (OCC (O) =O) CC1=C (C) N (C (C2=CC=C (Cl) C=C2) =O) C3=C1C=C (OC) C=C3
Molecular Formula
C21H18ClNO6
Molecular Weight
415.82
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
1H-Indole-3-acetic acid, 1- (4-chlorobenzoyl) -5-methoxy-2-methyl-, carboxymethyl ester
Available Sizes
Frequently Asked Questions
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