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Dyclonine hydrochloride

Dyclonine is an oral anaesthetic found in Sucrets, an over the counter throat lozenge. (In Vitro) :Dyclonine hydrochloride (50 μM; 24 h) sensitizes cancer cells to deficiency of cysteine and GSH.Dyclonine hydrochloride (0-2048 μg/mL; 24 or 48 h) shows significant bactericidal and fungicidal activity. (In Vivo) :Dyclonine hydrochloride (5 mg/kg; i.p.; single daily for 24 days) sensitizes the involucrin+ differentiated tumor cells to sulfasalazine treatment in vivo.Dyclonine hydrochloride (5 mg/kg; i.p.; single daily for 21 days) suppress the growth of tumors formed by ALDH3A1-expressing gastric cancer stemlike cells when combines with sulfasalazine.

Product Specifications

CAS Number

536-43-6

Product Name Alternative

Dyclonine Hydrochloride | Dyclonine HCL | Dyclone | Dyclothane | Tanaclone | Sucrets | Tanac

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Ethanol: 36 mg/mL (110.47 mM) ; Water: 6 mg/mL (18.41 mM) ; DMSO: 15 mg/mL (46.03 mM)

Smiles

CCCCOC1=CC=C (C=C1) C (=O) CCN2CCCCC2.Cl

Molecular Formula

C18H27NO2·HCl

Molecular Weight

325.87

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1- (4-butoxyphenyl) -3-piperidin-1-ylpropan-1-one; hydrochloride

Available Sizes

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