Valnemulin (hydrochloride)

Valnemulin hydrochloride is an orally effective truncated pleurotin antibiotic that inhibits protein synthesis in bacteria by binding to peptidyl transferase in the 50s ribosome subunit. Valnemulin hydrochloride effectively eliminates Mycobacterium bovis in the lungs in an experimental bovine model of Mycoplasma bovis infection. Valnemulin hydrochloride can reduce the mortality of epidemic rabbit enteropathy and has no adverse effect on the growth performance of rabbits[1][2].

Product Specifications

CAS Number

[133868-46-9]

UNSPSC

12352211

Hazard Statement

H302, H319, H335, H400, H410

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Valnemulin-Hydrochloride.html

Purity

98.13

Solubility

DMSO : ≥ 100 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

C[C@@H]([C@@H]([C@@](C)(C[C@H]1OC(CSC(C)(C)CNC([C@H](N)C(C)C)=O)=O)C=C)O)C(CCC2=O)(CC[C@H]3C)[C@]2([H])C31C.Cl

Molecular Formula

C31H53ClN2O5S

Molecular Weight

601.28

Precautions

H302, H319, H335, H400, H410

References & Citations

[1]L. Stipkovits, et al. The efficacy of valnemulin (Econor®) in the control of disease caused by experimental infection of calves with Mycoplasma bovis. Research in Veterinary Science, Volume 78, Issue 3, June 2005, Pages 207–215.|[2]Dip R, et al. Efficacy and tolerability of early administration of valnemulin hydrochloride premix on epizootic rabbit enteropathy. Vet J. 2015 Jun;204 (3) :309-14.