TOFA
TOFA (RMI14514, MDL14514) is an indirect, allosteric inhibitor of Acetyl-CoA carboxylase-α (ACCA) and fatty acid synthesis; converted to TOFyl-CoA, exerts an allosteric inhibition on ACCA; lowers blood lipids and inhibits fatty acid synthesis with minimal effects on liver weight and liver fat content; also induces human cancer cell apoptosis through disturbing their fatty acid synthesis.
Product Specifications
CAS Number
54857-86-2
Product Name Alternative
RMI14514 | MDL14514
Purity
>98% (HPLC)
Solubility
DMSO: ≥ 34 mg/mL
Smiles
CCCCCCCCCCCCCCOC1=CC=C (O1) C (=O) O
Molecular Formula
C19H32O4
Molecular Weight
324.45498
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2-Furancarboxylic acid, 5- (tetradecyloxy) -
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