AZD 2098
AZD2098 is a potent, selective, orally bioavailable CCR4 receptor antagonist with pIC50 of 7.8 for hCCR4, pIC50 of 8.0 for rCCR4; shows no significant activity against a panel of chemokine receptors (CXCR1, CXCR2, CCR1, CCR2b, CCR5, CCR7, CCR8; inactive at 10 uM) ; inhibits Th2 cell CCL22 driven chemotaxis in 0.3% HSA with pIC50 of 6.3; exhibits anti-inflammatory effects in Brown-Norway rats sensitized to ovalbumin.Asthma Phase 1 Clinical.
Product Specifications
CAS Number
566203-88-1
Product Name Alternative
AZD2098 | AZD-2098
Purity
>98% (HPLC)
Solubility
DMSO: Soluble (< 1 mg/ml refers to the product slightly soluble or insoluble)
Smiles
O=S (C1=CC=CC (Cl) =C1Cl) (NC2=NC=CN=C2OC) =O
Molecular Formula
C11H9Cl2N3O3S
Molecular Weight
334.171
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2,3-Dichloro-N- (3-methoxy-2-pyrazinyl) benzenesulfonamide
Available Sizes
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