Cefmetazole sodium

Cefmetazole sodium is a semisynthetic cephamycin antibiotic. Target: Antibacterial Cefmetazole sodium has a broad spectrum of activity comparable to that of the second-generation cephalosporins, covering gram-positive, gram-negative, and anaerobic bacteria. (In Vitro) :Cefmetazole sodium (Sodium cefmetazole) has antibiotic affinity to S. aureus with a MIC value of 1.0 mg/L and has affinity for PBP1, PBP2 and PBP3 with IC50 values of ≤0.3, 0.109 and 0.494 mg/L. (In Vivo) :Cefmetazole sodium (Sodium cefmetazole) (100 mg/kg; i.h.; twice a day, for 7 days; male ICR mice) alters gut bacterial flora.