Bufalin
Bufalin is an active ingredient and one of the glycosides in the traditional Chinese medicine ChanSu; it is also a bufadienolide toxin originally isolated from the venom of the Chinese toad Bufo gargarizans, with potential cardiotonic and antineoplastic activity. Although the mechanism of action of bufalin is still under investigation, this agent is a specific Na+/K+-ATPase inhibitor and can induce apoptosis in Y cell lines through the activation of the transcription factor AP-1 via a mitogen activated protein kinase (MAPK) pathway.
Product Specifications
CAS Number
465-21-4
Product Name Alternative
NSC 89595
Purity
>98% (HPLC)
Solubility
DMSO: 10 mM
Smiles
5- ((3S,5R,8R,9S,10S,13R,14S,17R) -3,14-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl) -2H-pyran-2-one
Molecular Formula
C24H34O4
Molecular Weight
386.52
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
5- ((3S,5R,8R,9S,10S,13R,14S,17R) -3,14-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl) -2H-pyran-2-one
Available Sizes
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