MK-0752
A potent γ-secretase inhibitor that shows dose-dependent reduction of Aβ40 with an IC50 of 5 nM in human SH-SY5Y cells; Notch signaling inhibitor.Breast Cancer Phase 2 Clinical.
Product Specifications
CAS Number
471905-41-6
Product Name Alternative
MK0752 | MK 0752
Purity
>98% (HPLC)
Solubility
10 mM in DMSO
Smiles
O=C (O) CC[C@H]1CC[C@] (C2=CC (F) =CC=C2F) (S (=O) (C3=CC=C (Cl) C=C3) =O) CC1
Molecular Formula
C21H21ClF2O4S
Molecular Weight
442.9038
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Cyclohexanepropanoic acid, 4-[ (4-chlorophenyl) sulfonyl]-4- (2,5-difluorophenyl) -, cis-
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