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MK-0752

A potent γ-secretase inhibitor that shows dose-dependent reduction of Aβ40 with an IC50 of 5 nM in human SH-SY5Y cells; Notch signaling inhibitor.Breast Cancer Phase 2 Clinical.

Product Specifications

CAS Number

471905-41-6

Product Name Alternative

MK0752 | MK 0752

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

O=C (O) CC[C@H]1CC[C@] (C2=CC (F) =CC=C2F) (S (=O) (C3=CC=C (Cl) C=C3) =O) CC1

Molecular Formula

C21H21ClF2O4S

Molecular Weight

442.9038

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Cyclohexanepropanoic acid, 4-[ (4-chlorophenyl) sulfonyl]-4- (2,5-difluorophenyl) -, cis-

Available Sizes

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