Purmorphamine
Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM.
Product Specifications
CAS Number
483367-10-8
Product Name Alternative
Purmorphamine
Purity
>98% (HPLC)
Solubility
DMSO: 4 mg/mL warmed (7.68 mM)
Smiles
N1 (C2CCCCC2) C=NC3=C (NC4=CC=C (N5CCOCC5) C=C4) N=C (OC6=C7C=CC=CC7=CC=C6) N=C13
Molecular Formula
C31H32N6O2
Molecular Weight
520.62
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
9-cyclohexyl-N- (4-morpholinophenyl) -2- (naphthalen-1-yloxy) -9H-purin-6-amine
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