Purmorphamine

Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM in HEK293T cell and also is an inducer of osteoblast differentiation with EC50 of 1 μM.

Product Specifications

CAS Number

483367-10-8

Product Name Alternative

Purmorphamine

Purity

>98% (HPLC)

Solubility

DMSO: 4 mg/mL warmed (7.68 mM)

Smiles

N1 (C2CCCCC2) C=NC3=C (NC4=CC=C (N5CCOCC5) C=C4) N=C (OC6=C7C=CC=CC7=CC=C6) N=C13

Molecular Formula

C31H32N6O2

Molecular Weight

520.62

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

9-cyclohexyl-N- (4-morpholinophenyl) -2- (naphthalen-1-yloxy) -9H-purin-6-amine

Available Sizes

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