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(+) -Bicuculline

Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species.

Product Specifications

CAS Number

485-49-4

Product Name Alternative

NSC 32192

Purity

>98% (HPLC)

Solubility

DMSO: 73 mg/mL warmed (198.72 mM)

Smiles

O=C1O[C@@H] ([C@H]2N (C) CCC3=CC4=C (OCO4) C=C23) C5=CC=C (OCO6) C6=C51

Molecular Formula

C20H17NO6

Molecular Weight

367.36

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

(R) -6- ((S) -6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinolin-5-yl) -[1,3]dioxolo[4,5-e]isobenzofuran-8 (6H) -one

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