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Cortisone acetate

Cortisone acetate (Cortisone 21-acetate) is a synthetic glucocorticoid corticosteroid and corticosteroid ester; the C21 acetate ester of cortisone and acts as a prodrug of cortisone in the body.Allergy Approved (In Vitro) :Cortisone (2.8-28,000 nM) dose-dependently attenuates the apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs) . (In Vivo) :Cortisone (2 mg/kg; i.m. on alternate days for 2 months) decreases the BCG (the vaccine strain of tubercle bacillus) lesions and tuberculin reactions in rabbits.

Product Specifications

CAS Number

50-04-4

Product Name Alternative

Cortisone 21-acetate

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

DMSO: 6.8 mg/mL (Need ultrasonic and warming)

Smiles

CC (=O) OCC (=O) [C@]1 (CC[C@@H]2[C@@]1 (CC (=O) [C@H]3[C@H]2CCC4=CC (=O) CC[C@]34C) C) O

Molecular Formula

C23H30O6

Molecular Weight

402.4807

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

Pregn-4-ene-3,11,20-trione, 21- (acetyloxy) -17-hydroxy- (9CI)

Available Sizes

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