Cortisone acetate
Cortisone acetate (Cortisone 21-acetate) is a synthetic glucocorticoid corticosteroid and corticosteroid ester; the C21 acetate ester of cortisone and acts as a prodrug of cortisone in the body.Allergy Approved (In Vitro) :Cortisone (2.8-28,000 nM) dose-dependently attenuates the apoptosis induced by Cortisol in peripheral-blood mononuclear cells (PBMCs) . (In Vivo) :Cortisone (2 mg/kg; i.m. on alternate days for 2 months) decreases the BCG (the vaccine strain of tubercle bacillus) lesions and tuberculin reactions in rabbits.
Product Specifications
CAS Number
50-04-4
Product Name Alternative
Cortisone 21-acetate
Field of Research
Pharmacology & Drug Discovery
Purity
>98% (HPLC)
Solubility
DMSO: 6.8 mg/mL (Need ultrasonic and warming)
Smiles
CC (=O) OCC (=O) [C@]1 (CC[C@@H]2[C@@]1 (CC (=O) [C@H]3[C@H]2CCC4=CC (=O) CC[C@]34C) C) O
Molecular Formula
C23H30O6
Molecular Weight
402.4807
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Pregn-4-ene-3,11,20-trione, 21- (acetyloxy) -17-hydroxy- (9CI)
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