BI-D1870
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B.
Product Specifications
CAS Number
501437-28-1
Product Name Alternative
BID1870 | BI D1870 | BI-D1870.
Purity
>98% (HPLC)
Solubility
DMSO:78 mg/mL (199.27 mM) ; Ethanol:<1 mg/mL (<1 mM) ; Water:<1 mg/mL (<1 mM)
Smiles
O=C1N (C) C2=CN=C (NC3=CC (F) =C (O) C (F) =C3) N=C2N (CCC (C) C) C1C
Molecular Formula
C19H23F2N5O2
Molecular Weight
391.42
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
2- ((3,5-difluoro-4-hydroxyphenyl) amino) -8-isopentyl-5,7-dimethyl-7,8-dihydropteridin-6 (5H) -one.
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