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KU-57788

A highly potent and selective DNA-PK inhibitor (IC50=14 nM) ; also modestly inhibits BRD4 and BRDT with IC50 of 1 uM and 3.5 uM respectively; also stimulates Cas9-mediated genome editing.

Product Specifications

CAS Number

503468-95-9

Product Name Alternative

KU 57788 | NU-7441 | KU57788 | NU7441 | NU 7441

Purity

>98% (HPLC)

Solubility

10 mM in DMSO

Smiles

O=C1C=C (N2CCOCC2) OC3=C (C4=C5C (C6=CC=CC=C6S5) =CC=C4) C=CC=C13

Molecular Formula

C25H19NO3S

Molecular Weight

413.4883

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

4H-1-Benzopyran-4-one, 8- (4-dibenzothienyl) -2- (4-morpholinyl) -

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