Vecuronium bromide

Vecuronium (bromide) is a muscle relaxant in the category of non-depolarizing blocking agents. (In Vitro) :Vecuronium bromide (0-100 μM, 15 min) inhibits [3H] norepinephrine (NE) uptake to 65% at 100 μM in adrenal medullary cells.Vecuronium bromide (0-15 μM,72 hours) inhibits cancer cell proliferation and migration in a concentration-dependent manner.Vecuronium bromide (0-15 μM,72 hours) can significantly reduce cell viability by combining with cisplatin. (In Vivo) :Vecuronium bromide (Intravenous injection, 0-5 μM, every 30 min, 2 hours) attenuates the response of carotid sinus nerve activity (CSNA) to hypoxia in a dose-dependent manner and inhibits the neural response of the carotid body to acetylcholine (ACh) in Wister rats.

Product Specifications

CAS Number

50700-72-6

Product Name Alternative

NC 45

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Ethanol: 100 mg/mL (156.8 mM) ; Water: 4 mg/mL (6.27 mM) ; DMSO: 100 mg/mL (156.8 mM)

Smiles

CC (O[C@@H]1[C@@H] (N2CCCCC2) C[C@]3 (C) [C@@]4 ([H]) CC[C@]5 (C) [C@H] (OC (C) =O) [C@@H] ([N+]6 (C) CCCCC6) C[C@@]5 ([H]) [C@]4 ([H]) CC[C@@]3 ([H]) C1) =O.[Br-]

Molecular Formula

C34H57BrN2O4

Molecular Weight

637.73

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1- ((2S,3S,5S,8R,9S,10S,13S,14S,16S,17S) -3,17-diacetoxy-10,13-dimethyl-2- (piperidin-1-yl) hexadecahydro-1H-cyclopenta[a]phenanthren-16-yl) -1-methylpiperidin-1-ium bromide