Pifithrin-β hydrobromide
A cyclic analog of Pifithrin-α and a small molecule inhibitor of p53; prevents dexamethasone-induced cell death in murine thymocytes with EC50 of 2.01 uM, sensitizes p53-deficient tumors to radiotherapy and chemotherapy and increases apoptosis in cancer cells.
Product Specifications
CAS Number
511296-88-1
Product Name Alternative
Cyclic Pifithrin-α hydrobromide | PFT-β hydrobromide
Purity
>98% (HPLC)
Solubility
DMSO: 26 mg/mL
Smiles
CC1=CC=C (C=C1) C2=CN3C4=C (CCCC4) SC3=N2.Br
Molecular Formula
C16H17BrN2S
Molecular Weight
349.2886
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Imidazo[2,1-b]benzothiazole, 5,6,7,8-tetrahydro-2- (4-methylphenyl) -, hydrobromide (1:1)
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