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Trifluridine

Trifluorothymidine (TFT) and is an inhibitor of thymidine phosphorylase. TFT also inhibits thymidylate synthase (TS), a rate-limiting enzyme of DNA biosynthesis, and is incorporated into DNA.

Product Specifications

CAS Number

70-00-8

Product Name Alternative

NSC 75520 | NSC 529182 | TFT | Trifluridine

Field of Research

Pharmacology & Drug Discovery

Purity

>98% (HPLC)

Solubility

Ethanol: 59 mg/mL (199.18 mM) ; Water: 59 mg/mL (199.18 mM) ; DMSO: 59 mg/mL (199.18 mM)

Smiles

O=C1NC (C (C (F) (F) F) =CN1[C@@H]2O[C@H] (CO) [C@@H] (O) C2) =O

Molecular Formula

C10H11F3N2O5

Molecular Weight

296.2

Storage Conditions

Storage temperature: -20°C. Stability: ≥ 2 years

Notes

For research use only.

Other Product Names

1- ((2R,4S,5R) -4-hydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) -5- (trifluoromethyl) pyrimidine-2,4 (1H,3H) -dione.

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